1807530-10-4

1807530-10-4 structure

Name: Azido-PEG3-aldehyde
Chemical Name: Azido-PEG3-aldehyde
CAS Number: 1807530-10-4
Molecular Formula: C₉H₁₇N₃O₄
Molecular Weight: 231.249
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-07 03:18:48
Modify Date: 2024-01-10 10:03:13
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG3-aldehyde
Synonyms	N3-PEG3-ALD

Description	Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562