26124-78-7

26124-78-7 structure
26124-78-7 structure
  • Name: Poly-L-lysine hydrochloride
  • Chemical Name: POLY-L-LYSINE HYDROCHLORIDE
  • CAS Number: 26124-78-7
  • Molecular Formula: (C6H14N2O2)x.(HCl)x
  • Molecular Weight:
  • Catalog: Biochemical Amino acids and their derivatives Lysine derivative
  • Create Date: 2018-11-01 12:55:00
  • Modify Date: 2024-01-02 20:07:08
  • Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1].

Name POLY-L-LYSINE HYDROCHLORIDE
Synonyms MFCD00081870
Description Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1].
Related Catalog
In Vitro Poly-L-lysine is a food-grade antimicrobial peptide that forms complexes with proteins. Such complexes are potential carriers for targeted delivery of agents. Electrostatic potential modelling of EPL was employed to describe the interaction affinity. A three-dimensional phase boundary curve was established which divided the complexation into a nano-scale and phase separation[2].
References

[1]. Archishman Ghosh, et al. Three archetypical classes of macromolecular regulators of protein liquid-liquid phase separation. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19474-19483.

[2]. Liang Guo, et al. pH-induced structural transition during complexation and precipitation of sodium caseinate and ε-Poly-l-lysine. Int J Biol Macromol. 2020 Jul 1;154:644-653.

Molecular Formula (C6H14N2O2)x.(HCl)x
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3