1235514-15-4

1235514-15-4 structure

Name: Boc-Aminooxy-PEG3-azide
Chemical Name: t-Boc-Aminoxy-PEG3-Azide
CAS Number: 1235514-15-4
Molecular Formula: C₁₃H₂₆N₄O₆
Molecular Weight: 334.369
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-27 14:57:26
Modify Date: 2024-01-28 08:32:57
Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	t-Boc-Aminoxy-PEG3-Azide
Synonyms	Carbamic acid, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester MFCD28950781 2-Methyl-2-propanyl (2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethoxy)carbamate

Description	Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.