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1334169-96-8

1334169-96-8 structure
1334169-96-8 structure
  • Name: Amino-PEG8-hydrazide-Boc
  • Chemical Name: Amino-PEG8-t-Boc-Hydrazide
  • CAS Number: 1334169-96-8
  • Molecular Formula: C24H49N3O11
  • Molecular Weight: 555.65936
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-17 09:46:32
  • Modify Date: 2024-01-08 12:28:51
  • Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Amino-PEG8-t-Boc-Hydrazide
Synonyms MFCD21363303
Description Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C24H49N3O11
Molecular Weight 555.65936