1422540-98-4

1422540-98-4 structure

Name: Azido-PEG4-4-nitrophenyl carbonate
Chemical Name: Azido-PEG4-4-nitrophenyl carbonate
CAS Number: 1422540-98-4
Molecular Formula: C₁₅H₂₀N₄O₈
Molecular Weight: 384.341
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-22 08:32:19
Modify Date: 2024-01-02 07:47:34
Azido-PEG4-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG4-4-nitrophenyl carbonate
Synonyms	AZIDO-PEG4-4-NITROPHENYL CARBONATE

Description	Azido-PEG4-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562