1603845-32-4

1603845-32-4 structure

Name: TX1-85-1
Chemical Name: TX-85-1
CAS Number: 1603845-32-4
Molecular Formula: C₃₂H₃₆N₈O₃
Molecular Weight: 580.679999999999
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2018-06-24 06:58:40
Modify Date: 2024-01-07 20:29:17
TX1-85-1 is a Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling[1].

Name	TX-85-1

Description	TX1-85-1 is a Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	ErbB3:23 nM (IC50)
References	[1]. Xie T, et al. Pharmacological targeting of the pseudokinase Her3. Nat Chem Biol. 2014 Dec;10(12):1006-12.