1778219-81-0

1778219-81-0 structure

Name: m-PEG3-Boc
Chemical Name: m-PEG3-t-butyl ester
CAS Number: 1778219-81-0
Molecular Formula: C₁₂H₂₄O₅
Molecular Weight: 248.32
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-12-02 19:04:43
Modify Date: 2024-01-03 15:18:23
m-PEG3-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG3-t-butyl ester

Description	m-PEG3-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.