1807503-89-4

1807503-89-4 structure
1807503-89-4 structure
  • Name: BnO-PEG4-Boc
  • Chemical Name: Benzyl-PEG5-CH2CO2tBu
  • CAS Number: 1807503-89-4
  • Molecular Formula: C21H34O7
  • Molecular Weight: 398.491
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-05 18:46:39
  • Modify Date: 2024-01-10 15:08:31
  • BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Benzyl-PEG5-CH2CO2tBu
Synonyms 2-Methyl-2-propanyl 1-phenyl-2,5,8,11,14-pentaoxahexadecan-16-oate
MFCD28122960
2,5,8,11,14-Pentaoxahexadecan-16-oic acid, 1-phenyl-, 1,1-dimethylethyl ester
Description BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 472.2±40.0 °C at 760 mmHg
Molecular Formula C21H34O7
Molecular Weight 398.491
Flash Point 201.2±27.4 °C
Exact Mass 398.230438
LogP 2.16
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.484