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1807503-90-7

1807503-90-7 structure
1807503-90-7 structure
  • Name: Ald-Ph-PEG2-NH-Boc
  • Chemical Name: Ald-Ph-PEG2-NHBoc
  • CAS Number: 1807503-90-7
  • Molecular Formula: C19H28N2O6
  • Molecular Weight: 380.435
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-02 01:13:18
  • Modify Date: 2024-01-09 16:48:47
  • Ald-Ph-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-Ph-PEG2-NHBoc
Synonyms ALD-PH-PEG2-NH-BOC
Description Ald-Ph-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 581.3±50.0 °C at 760 mmHg
Molecular Formula C19H28N2O6
Molecular Weight 380.435
Flash Point 305.4±30.1 °C
Exact Mass 380.194733
LogP 1.57
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.526