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1807520-99-5

1807520-99-5 structure
1807520-99-5 structure
  • Name: DNP-PEG4-alcohol
  • Chemical Name: DNP-PEG4-alcohol
  • CAS Number: 1807520-99-5
  • Molecular Formula: C14H21N3O8
  • Molecular Weight: 359.332
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-07 01:30:11
  • Modify Date: 2024-01-09 18:58:35
  • DNP-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DNP-PEG4-alcohol
Synonyms MFCD28385460
Ethanol, 2-[2-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]ethoxy]-
2-[2-(2-{2-[(2,4-Dinitrophenyl)amino]ethoxy}ethoxy)ethoxy]ethanol
Description DNP-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.4±0.1 g/cm3
Boiling Point 557.1±50.0 °C at 760 mmHg
Molecular Formula C14H21N3O8
Molecular Weight 359.332
Flash Point 290.7±30.1 °C
Exact Mass 359.132874
LogP 0.73
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.580