1807540-88-0

1807540-88-0 structure
1807540-88-0 structure
  • Name: Ald-Ph-amido-C2-PEG3-azide
  • Chemical Name: Ald-Ph-PEG3-Azide
  • CAS Number: 1807540-88-0
  • Molecular Formula: C16H22N4O5
  • Molecular Weight: 350.370
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-24 22:37:34
  • Modify Date: 2024-01-08 22:07:18
  • Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald-Ph-PEG3-Azide
Synonyms ALD-PH-PEG3-N3
Description Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C16H22N4O5
Molecular Weight 350.370
Exact Mass 350.159027
LogP 0.29
Hazard Codes Xi