2151823-08-2

2151823-08-2 structure

Name: m-PEG24-NH2
Chemical Name: Methly-PEG24-Amine
CAS Number: 2151823-08-2
Molecular Formula: C₄₉H₁₀₁NO₂₄
Molecular Weight: 1088.33
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-12-16 17:01:46
Modify Date: 2024-01-09 21:16:58
m-PEG24-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methly-PEG24-Amine

Description	m-PEG24-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562