452072-20-7

452072-20-7 structure

Name: SPP-DM1
Chemical Name: DM1-SPP
CAS Number: 452072-20-7
Molecular Formula: C₄₄H₅₉ClN₄O₁₄S₂
Molecular Weight: 967.541
Catalog: Research Areas Cancer
Create Date: 2018-06-03 16:19:58
Modify Date: 2024-03-04 21:15:01
SPP-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].

Name	DM1-SPP

Description	SPP-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].
Related Catalog	Research Areas >> Cancer
Target	Maytansinoids
References	[1]. Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules.