65428-13-9

65428-13-9 structure

Name: 1-Methoxyphaseollidin
Chemical Name: 1-methoxyphaseollidin
CAS Number: 65428-13-9
Molecular Formula: C₂₁H₂₂O₅
Molecular Weight: 354.39638
Catalog: Natural product Phenols
Create Date: 2018-10-16 17:07:39
Modify Date: 2024-01-22 11:17:07
1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].

Name	1-methoxyphaseollidin
Synonyms	EINECS 2017-001-1

Description	1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Human Endogenous Metabolite
References	[1]. Fukai T, et, al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63. [2]. Nagumo S, et, al. Inhibition of lysoPAF acetyltransferase activity by components of licorice root. Biol Pharm Bull. 1999 Oct;22(10):1144-6. [3]. Sinha SK, et, al. Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. Comb Chem High Throughput Screen. 2021;24(4):591-597.

Hazard Codes	Xi