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787524-78-1

787524-78-1 structure
787524-78-1 structure
  • Name: m-PEG4-sulfonic acid
  • Chemical Name: m-PEG4-sulfonic acid
  • CAS Number: 787524-78-1
  • Molecular Formula: C9H20O7S
  • Molecular Weight: 272.316
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-13 12:39:32
  • Modify Date: 2024-01-10 21:52:57
  • m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG4-sulfonic acid
Synonyms MFCD29042380
2,5,8,11-Tetraoxatridecane-13-sulfonic acid
Description m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Molecular Formula C9H20O7S
Molecular Weight 272.316
Exact Mass 272.092987
LogP -2.95
Index of Refraction 1.464