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  • BioBioPha
  • China
  • Product Name: Kushenol B
  • Price: ¥3900.0/5mg
  • Purity: 96.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng

99217-64-8

99217-64-8 structure
99217-64-8 structure
  • Name: Kushenol B
  • Chemical Name: Kushenol B
  • CAS Number: 99217-64-8
  • Molecular Formula: C30H36O6
  • Molecular Weight: 492.603
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
  • Create Date: 2019-01-10 17:33:41
  • Modify Date: 2024-01-21 12:03:22
  • Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].

Name Kushenol B
Synonyms 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6-(3-methyl-2-buten-1-yl)-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)-
(2S)-2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
Description Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].
Related Catalog
Target

IC50: 31 µM (cAMP PDE)[1]

References

[1]. Han-Tian Fan, et al. The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening. Mol Med Rep

Density 1.2±0.1 g/cm3
Boiling Point 702.3±60.0 °C at 760 mmHg
Molecular Formula C30H36O6
Molecular Weight 492.603
Flash Point 228.2±26.4 °C
Exact Mass 492.251190
LogP 8.61
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.605