1599440-13-7

1599440-13-7 structure

Name: Deruxtecan analog
Chemical Name: Deruxtecan analog
CAS Number: 1599440-13-7
Molecular Formula: C₅₂H₅₆FN₉O₁₃
Molecular Weight: 1034.05
Catalog: Signaling Pathways Antibody-drug Conjugate Drug-Linker Conjugates for ADC
Create Date: 2018-08-29 15:19:34
Modify Date: 2024-01-08 12:59:28
Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC) extracted from patent WO2017002776A1, compound 1.

Name	Deruxtecan analog

Description	Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC) extracted from patent WO2017002776A1, compound 1.
Related Catalog	Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC Research Areas >> Cancer
Target	Drug-linker conjugates for ADC[1]
In Vitro	Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window[2].
References	[1]. NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1. [2]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.