154446-98-7

154446-98-7 structure

154446-98-7 structure

Name: LY 222306
Chemical Name: LY 222306
CAS Number: 154446-98-7
Molecular Formula: C₁₉H₂₃N₅O₇
Molecular Weight: 433.42
Catalog: Research Areas Cancer
Create Date: 2019-02-08 10:52:36
Modify Date: 2024-01-12 21:16:31
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

Name	LY 222306

Description	LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
Target	Ki: 0.77 nM (GARFT)[1]
References	[1]. Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.

Molecular Formula	C₁₉H₂₃N₅O₇
Molecular Weight	433.42