Name | GPR4 antagonist 3 |
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Description | GPR4 antagonist 3 is a selective, and orally available GPR4 antagonist with an IC50 of 70 nM[1]. Anti-inflammatory activities[1]. |
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Related Catalog | |
Target |
IC50: 70 nM (GPR4)[1]. |
In Vivo | GPR4 antagonist 3 shows a significant anti-inflammatory effect in the rat antigen induced arthritis model after oral administration at 30 mg/kg bid[1].GPR4 antagonist 3 also prevents angiogenesis in the mouse chamber model as well as pain as demonstrated in the rat complete Freund’s adjuvant model[1]. |
References |
Molecular Formula | C24H28N6O |
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Molecular Weight | 416.52 |