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2158297-63-1

2158297-63-1 structure
2158297-63-1 structure
  • Name: KRAS G12C inhibitor 11
  • Chemical Name: KRAS G12C inhibitor 5
  • CAS Number: 2158297-63-1
  • Molecular Formula: C32H37N7O2
  • Molecular Weight: 551.68
  • Catalog: Signaling Pathways GPCR/G Protein Ras
  • Create Date: 2019-03-03 17:44:07
  • Modify Date: 2024-01-06 10:19:17
  • KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].

Name KRAS G12C inhibitor 5
Description KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1].
Related Catalog
Target

KRas G12C[1]

In Vitro Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].
References

[1]. John P. Fischer, et al. Kras g12c inhibitors. WO2017201161A1.

Molecular Formula C32H37N7O2
Molecular Weight 551.68