2036074-41-4

2036074-41-4 structure

Name: AMPA Receptor Modulator-1
Chemical Name: AMPA Receptor Modulator
CAS Number: 2036074-41-4
Molecular Formula: C₁₆H₁₁ClF₃NO₂
Molecular Weight: 341.71
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2019-03-30 21:05:34
Modify Date: 2024-01-09 14:00:11
AMPA Receptor Modulator is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].

Name	AMPA Receptor Modulator

Description	AMPA Receptor Modulator is a potent, oral active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	pIC50: 9.7 (TARP γ-8)[1]
References	[1]. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.

Molecular Formula	C₁₆H₁₁ClF₃NO₂
Molecular Weight	341.71