1704740-52-2

1704740-52-2 structure

Name: AZ PFKFB3 26
Chemical Name: AZ PFKFB3 26
CAS Number: 1704740-52-2
Molecular Formula: C₂₄H₂₆N₄O₂
Molecular Weight: 402.49
Catalog: Research Areas Cancer
Create Date: 2019-07-28 09:22:41
Modify Date: 2024-01-08 12:09:36
AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1].

Name	AZ PFKFB3 26

Description	AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 23 nM (PFKFB3), 2.06 μM (PFKFB1), 0.384 μM (PFKFB2)[1]
References	[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015 Apr 23;58(8):3611-25.