2244684-49-7
2244684-49-7 structure
- Name: CM 11
- Chemical Name: Homo-PROTAC pVHL30 degrader 1
- CAS Number: 2244684-49-7
- Molecular Formula: C58H82N8O14S2
- Molecular Weight: 1179.45
- Catalog: Signaling Pathways PROTAC PROTAC
- Create Date: 2019-06-04 18:06:07
- Modify Date: 2024-01-08 17:34:51
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Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC[1].
| Name | Homo-PROTAC pVHL30 degrader 1 |
|---|
| Description | Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC[1]. |
|---|---|
| Related Catalog | |
| Target |
pVHL30[1] PROTAC[1] |
| In Vitro | Homo-PROTAC pVHL30 degrader 1 dimerizes von Hippel-Lindau (VHL) with high avidity in vitro and induces potent, rapid and proteasome-dependent self-degradation of VHL in different cell lines, in a highly isoform-selective fashion and without triggering a hypoxic response[1]. |
| References |
| Molecular Formula | C58H82N8O14S2 |
|---|---|
| Molecular Weight | 1179.45 |
| Storage condition | 2-8℃ |