1221349-53-6
1221349-53-6 structure
- Name: TC-I 2014
- Chemical Name: TC-I 2014
- CAS Number: 1221349-53-6
- Molecular Formula: C23H19F6N3O
- Molecular Weight: 467.41
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
- Create Date: 2019-06-02 09:03:13
- Modify Date: 2024-01-13 17:03:07
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TC-I 2014 (compound 5) is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models[1].
| Name | TC-I 2014 |
|---|
| Description | TC-I 2014 (compound 5) is a potent Benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonist, with IC50 values of 0.8 nM, 3.0 nM and 4.4 nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models[1]. |
|---|---|
| Related Catalog | |
| Target |
TRPM8[1]. |
| References |
| Molecular Formula | C23H19F6N3O |
|---|---|
| Molecular Weight | 467.41 |