720691-69-0

720691-69-0 structure

Name: GSK-239512
Chemical Name: GSK-239512
CAS Number: 720691-69-0
Molecular Formula: C₂₃H₂₇N₃O₂
Molecular Weight: 377.479
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2019-06-16 18:29:01
Modify Date: 2024-01-12 12:44:48
GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].

Name	GSK-239512
Synonyms	2-Pyrrolidinone, 1-[6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]- MFCD27922168 GSK-239512 1-{6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}-2-pyrrolidinone

Description	GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	H3 receptor
References	[1]. Grove RA, et, al. A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer's disease. Curr Alzheimer Res. 2014 Jan;11(1):47-58.