1567335-29-8

1567335-29-8 structure

Name: Cav 2.2 blocker 1
Chemical Name: Cav 2.2 blocker 1
CAS Number: 1567335-29-8
Molecular Formula: C₂₅H₂₉ClN₂O₂
Molecular Weight: 424.96
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2019-06-30 23:53:15
Modify Date: 2024-01-06 19:14:09
Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].

Name	Cav 2.2 blocker 1

Description	Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Neurological Disease
Target	IC50: 1 nM (Cav 2.2)[1].
References	[1]. Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783.