Name | BI-0252 |
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Description | BI-0252 is an orally active, selective MDM2-p53 inhibitor with an IC50 of 4 nM. BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft, with concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis[1]. |
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Related Catalog | |
Target |
IC50: 4 nM (MDM2-p53)[1] |
References |
Molecular Formula | C30H26Cl2FN3O3 |
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Molecular Weight | 566.45 |