1451741-22-2

1451741-22-2 structure
1451741-22-2 structure
  • Name: FD 12-9
  • Chemical Name: FD 12-9
  • CAS Number: 1451741-22-2
  • Molecular Formula: C51H47N3O11
  • Molecular Weight: 877.93
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel BCRP
  • Create Date: 2019-08-04 13:59:58
  • Modify Date: 2024-01-12 16:31:36
  • FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].

Name FD 12-9
Description FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].
Related Catalog
Target

EC50: 0.9 nM (BCRP), 285 nM (P-gp)[1]

References

[1]. Hu Xuesen, et al. Developing a novel strategy to treat glioblastoma : improving brain bioavailability of sorafenib with a synthetic flavonoid dimer to inhibit drug efflux in blood brain barrier.

Molecular Formula C51H47N3O11
Molecular Weight 877.93