1430114-34-3

1430114-34-3 structure

Name: BMS-962212
Chemical Name: BMS-962212
CAS Number: 1430114-34-3
Molecular Formula: C₃₂H₂₈ClFN₈O₅
Molecular Weight: 659.07
Catalog: Signaling Pathways Metabolic Enzyme/Protease Factor Xa
Create Date: 2019-09-09 13:32:50
Modify Date: 2024-01-03 18:08:31
BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1].

Name	BMS-962212

Description	BMS-962212 is a direct, reversible, selective factor XIa (FXIa) inhibitor . BMS-962212 is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time, and decreases exposure dependently in FXI clotting activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa
References	[1]. Perera V, et al. First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects. Br J Clin Pharmacol. 2018 May;84(5):876-887.

Molecular Formula	C₃₂H₂₈ClFN₈O₅
Molecular Weight	659.07