Name | hGPR91 antagonist 1 |
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Description | HGPR91 antagonist 1 is a potent and selective small molecule hGPR91 antagonist with an IC50 of 7 μM[1]. |
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Related Catalog | |
Target |
IC50: 7 μM (HGPR91)[1] |
In Vivo | HGPR91 antagonist 1 leads to 59, 76% inhibition of ΔMAP at 2, 4 hours and has shown rat plasma protein binding 99%. HGPR91 antagonist 1 has engaged the target under the in vivo condition. HGPR91 antagonist 1 has clearance (CL) of 0.2 nmol/min/mg of RLM[1]. Animal Model: Wistar rats[1] Dosage: 100 mg/kg Administration: I.p.; 2 and 4 hours Result: Led to 59 and 76% inhibition of ΔMAP at 2 and 4 hours. |
References |
Molecular Formula | C31H23F4N3O |
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Molecular Weight | 529.53 |