1593478-56-8

1593478-56-8 structure

Name: (R)-CE3F4
Chemical Name: (R)-CE3F4
CAS Number: 1593478-56-8
Molecular Formula: C₁₁H₁₀Br₂FNO
Molecular Weight: 351.01
Catalog: Research Areas Others
Create Date: 2019-09-07 18:57:18
Modify Date: 2024-01-10 19:19:57
(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].

Name	(R)-CE3F4

Description	(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Courilleau D, et al. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1). Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8.

Molecular Formula	C₁₁H₁₀Br₂FNO
Molecular Weight	351.01