936616-33-0

936616-33-0 structure

Name: mu-conotoxin
Chemical Name: mu-conotoxin
CAS Number: 936616-33-0
Molecular Formula: C₉₂H₁₃₉N₃₅O₂₈S₆
Molecular Weight: 2375.70
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2019-10-08 17:34:52
Modify Date: 2024-01-04 04:07:54
μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. μ-Conotoxin-CnIIIC is a potent and persistent blocker of NaV1.4 channel. μ-Conotoxin-CnIIIC has analgesic, anaesthetic and myorelaxant properties[1][2].

Name	mu-conotoxin

Description	μ-Conotoxin-CnIIIC is a 22-residue conopeptide that can be isolated from Conus consors. μ-Conotoxin-CnIIIC is a potent and persistent blocker of NaV1.4 channel. μ-Conotoxin-CnIIIC has analgesic, anaesthetic and myorelaxant properties[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Inflammation/Immunology
Target	NaV1.4 Channel[2]
References	[1]. Markgraf R, et al. Mechanism and molecular basis for the sodium channel subtype specificity of µ-conopeptide CnIIIC. Br J Pharmacol. 2012 Oct;167(3):576-86. [2]. Del Río-Sancho S, et al. Cutaneous iontophoresis of μ-conotoxin CnIIIC-A potent NaV1.4 antagonist with analgesic, anaesthetic and myorelaxant properties. Int J Pharm. 2017 Feb 25;518(1-2):59-65.