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1036969-20-6

1036969-20-6 structure
1036969-20-6 structure
  • Name: CL2-SN-38
  • Chemical Name: CL2-SN-38
  • CAS Number: 1036969-20-6
  • Molecular Formula: C83H107N11O23
  • Molecular Weight: 1626.80
  • Catalog: Signaling Pathways Antibody-drug Conjugate Drug-Linker Conjugates for ADC
  • Create Date: 2019-10-13 11:57:29
  • Modify Date: 2024-02-04 16:02:34
  • CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types[1].

Name CL2-SN-38
Description CL2-SN-38 is a part of the antibody drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. The anti-Trop-2 hRS7-CL2A-SN-38 ADC provides significant and specific antitumor effects against a range of human solid tumor types[1].
Related Catalog
References

[1]. Cardillo TM, et al. Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. Clin Cancer Res. 2011 May 15;17(10):3157-69.

Molecular Formula C83H107N11O23
Molecular Weight 1626.80