1310327-20-8

1310327-20-8 structure

Name: Boc-NH-PEG2-C2-amido-C4-acid
Chemical Name: PROTAC Linker 30
CAS Number: 1310327-20-8
Molecular Formula: C₁₇H₃₂N₂O₇
Molecular Weight: 376.45
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-10-09 12:24:29
Modify Date: 2024-01-07 14:47:58
PROTAC Linker 30 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 30 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	PROTAC Linker 30

Description	PROTAC Linker 30 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 30 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.