Boc-NH-PEG2-C2-amido-C4-acid

Modify Date: 2024-01-07 14:47:58

Boc-NH-PEG2-C2-amido-C4-acid Structure
Boc-NH-PEG2-C2-amido-C4-acid structure
Common Name Boc-NH-PEG2-C2-amido-C4-acid
CAS Number 1310327-20-8 Molecular Weight 376.45
Density N/A Boiling Point N/A
Molecular Formula C17H32N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-NH-PEG2-C2-amido-C4-acid


PROTAC Linker 30 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 30 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 30

 Boc-NH-PEG2-C2-amido-C4-acid Biological Activity

Description PROTAC Linker 30 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 30 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.

 Chemical & Physical Properties

Molecular Formula C17H32N2O7
Molecular Weight 376.45
Storage condition 2-8°C