Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CHK1-IN-4
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2120398-41-4

2120398-41-4 structure

2120398-41-4 structure

Name: CHK1-IN-4
Chemical Name: CHK1-IN-4
CAS Number: 2120398-41-4
Molecular Formula: C₁₈H₁₈BrN₇O₂
Molecular Weight: 444.29
Catalog: Research Areas Cancer
Create Date: 2019-12-08 17:40:19
Modify Date: 2024-01-09 19:05:50
CHK1-IN-4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity[1].

Name	CHK1-IN-4

Description	CHK1-IN-4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity[1].
Related Catalog	Research Areas >> Cancer
Target	Chk1
In Vivo	CHK1-IN-4 (Compound 3) (40 mg/kg, IV, twice a week) alone enhances anti-tumor growth activity of CPT1 in the tumor model[1].
References	[1]. Xiong Cai, et al. 3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (chk1) inhibitors, and their preparations and applications. WO2017132928A1.

Molecular Formula	C₁₈H₁₈BrN₇O₂
Molecular Weight	444.29