Name | CHK1-IN-3 |
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Description | CHK1-IN-3 is a Checkpoint Kinase 1 (CHK1) inhibitor with an IC50 of 0.4 nM[1]. |
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Related Catalog | |
Target |
Chk1:0.4 nM (IC50) |
In Vitro | CHK1-IN-3 effectively inhibites the growth of malignant hematopathy cell lines especially Z-138 (IC50: 0.013 µM) and displays low affinity for hERG (IC50 > 40 µM)[1]. |
In Vivo | CHK1-IN-3 significantly suppresses the tumor growth in Z-138 cell inoculated xenograft model as a single agent with body weight unaffected[1]. |
References |
Molecular Formula | C20H23N9O |
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Molecular Weight | 405.46 |