596108-59-7
596108-59-7 structure
- Name: Aminopeptidase N Inhibitor
- Chemical Name: [3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid
- CAS Number: 596108-59-7
- Molecular Formula: C17H10N2O8
- Molecular Weight: 370.270
- Create Date: 2020-01-11 14:23:34
- Modify Date: 2024-01-02 11:21:25
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Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).
| Name | [3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid |
|---|---|
| Synonyms |
3-nitro-2-(2-nitrophenyl)-4-oxo-4H-1-benzopyran-8-acetic acid
[3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid 4H-1-Benzopyran-8-acetic acid, 3-nitro-2-(2-nitrophenyl)-4-oxo- |
| Description | Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M). |
|---|---|
| In Vitro | Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), ��-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 ��M. |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 591.6±50.0 °C at 760 mmHg |
| Molecular Formula | C17H10N2O8 |
| Molecular Weight | 370.270 |
| Flash Point | 311.6±30.1 °C |
| Exact Mass | 370.043701 |
| LogP | 1.17 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.702 |