Aminopeptidase N Inhibitor

Modify Date: 2024-01-02 11:21:25

Aminopeptidase N Inhibitor Structure
Aminopeptidase N Inhibitor structure
Common Name Aminopeptidase N Inhibitor
CAS Number 596108-59-7 Molecular Weight 370.270
Density 1.6±0.1 g/cm3 Boiling Point 591.6±50.0 °C at 760 mmHg
Molecular Formula C17H10N2O8 Melting Point N/A
MSDS N/A Flash Point 311.6±30.1 °C

 Use of Aminopeptidase N Inhibitor


Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).

 Names

Name [3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid
Synonym More Synonyms

 Aminopeptidase N Inhibitor Biological Activity

Description Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).
In Vitro Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 ��M).It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), ��-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 ��M.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 591.6±50.0 °C at 760 mmHg
Molecular Formula C17H10N2O8
Molecular Weight 370.270
Flash Point 311.6±30.1 °C
Exact Mass 370.043701
LogP 1.17
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.702

 Synonyms

3-nitro-2-(2-nitrophenyl)-4-oxo-4H-1-benzopyran-8-acetic acid
[3-Nitro-2-(2-nitrophenyl)-4-oxo-4H-chromen-8-yl]acetic acid
4H-1-Benzopyran-8-acetic acid, 3-nitro-2-(2-nitrophenyl)-4-oxo-