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912798-81-3

912798-81-3 structure
912798-81-3 structure
  • Name: LDN-75654
  • Chemical Name: N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide
  • CAS Number: 912798-81-3
  • Molecular Formula: C13H12ClFN2O2
  • Molecular Weight: 282.698
  • Create Date: 2020-01-11 17:32:26
  • Modify Date: 2024-01-06 19:36:53
  • LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice.

Name N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide
Synonyms 3-Isoxazolecarboxamide, N-(3-chloro-4-fluorophenyl)-5-(1-methylethyl)-
N-(3-Chloro-4-fluorophenyl)-5-isopropyl-1,2-oxazole-3-carboxamide
Description LDN-75654 is a novel potent SMN2 modulator (EC50=1.8 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice.
References References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. View Related Products by Target SMN2 Modulator
Density 1.3±0.1 g/cm3
Boiling Point 327.9±42.0 °C at 760 mmHg
Molecular Formula C13H12ClFN2O2
Molecular Weight 282.698
Flash Point 152.1±27.9 °C
Exact Mass 282.057129
LogP 3.51
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.582