1448189-98-7
1448189-98-7 structure
- Name: VHL Ligand 3
- Chemical Name: 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
- CAS Number: 1448189-98-7
- Molecular Formula: C27H38N4O5S
- Molecular Weight: 530.679
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2020-01-11 16:34:59
- Modify Date: 2024-01-13 12:48:41
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A VHL ligand for PROTAC.
| Name | 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
|---|---|
| Synonyms |
L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
| Description | A VHL ligand for PROTAC. |
|---|---|
| References | References 1. Wurz RP, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01781. 2. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. View Related Products by Target E3 Ligase Ligand |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 755.7±60.0 °C at 760 mmHg |
| Molecular Formula | C27H38N4O5S |
| Molecular Weight | 530.679 |
| Flash Point | 410.9±32.9 °C |
| Exact Mass | 530.256287 |
| LogP | 2.63 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.572 |
| Hazard Codes | Xi |
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