Name | 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
---|---|
Synonyms |
L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
Description | A VHL ligand for PROTAC. |
---|---|
References | References 1. Wurz RP, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01781. 2. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. View Related Products by Target E3 Ligase Ligand |
Density | 1.2±0.1 g/cm3 |
---|---|
Boiling Point | 755.7±60.0 °C at 760 mmHg |
Molecular Formula | C27H38N4O5S |
Molecular Weight | 530.679 |
Flash Point | 410.9±32.9 °C |
Exact Mass | 530.256287 |
LogP | 2.63 |
Vapour Pressure | 0.0±2.7 mmHg at 25°C |
Index of Refraction | 1.572 |
Hazard Codes | Xi |
---|