1784252-84-1
1784252-84-1 structure
- Name: C 021 dihydrochloride
- Chemical Name: 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride
- CAS Number: 1784252-84-1
- Molecular Formula: C27H41N5O2.2HCl
- Molecular Weight: 540.569
- Catalog: Signaling Pathways GPCR/G Protein CCR
- Create Date: 2020-01-11 17:38:35
- Modify Date: 2024-04-05 01:21:16
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C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.
| Name | 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride |
|---|---|
| Synonyms |
MFCD16618393
2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine dihydrochloride 2-(1,4'-Bipiperidin-1'-yl)-N-cycloheptyl-6,7-dimethoxy-4-quinazolinamine dihydrochloride 4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-, hydrochloride (1:2) |
| Description | C-021 dihydrochloride is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively. |
|---|---|
| References | References 1. Yokoyama K, et al. Bioorg Med Chem. 2009 Jan 1;17(1):64-73. View Related Products by Target Chemokine Receptor (CCR and CXCR) |
| Molecular Formula | C27H41N5O2.2HCl |
|---|---|
| Molecular Weight | 540.569 |
| Exact Mass | 539.279358 |
| Storage condition | 2-8°C |