1235575-97-9
1235575-97-9 structure
- Name: DS-5272
- Chemical Name: DS-5272
- CAS Number: 1235575-97-9
- Molecular Formula: C34H38Cl2F2N6O2S
- Molecular Weight: 703.675
- Create Date: 2020-01-20 12:57:56
- Modify Date: 2024-01-15 00:14:36
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A potent and orally active p53-MDM2 interaction inhibitor with IC50 of 2.4 nM; inhibits SJSA-1 cell proliferation with GI50 of 0.17 uM, demonstrates excellent antitumor efficacy on SJSA-1 xenografted models with high safety and good PK profiles.
| Name | DS-5272 |
|---|
| Description | A potent and orally active p53-MDM2 interaction inhibitor with IC50 of 2.4 nM; inhibits SJSA-1 cell proliferation with GI50 of 0.17 uM, demonstrates excellent antitumor efficacy on SJSA-1 xenografted models with high safety and good PK profiles. |
|---|---|
| References | References 1. Miyazaki M, et al. Bioorg Med Chem. 2015 May 15;23(10):2360-7. View Related Products by Target MDM2-p53 |
| Molecular Formula | C34H38Cl2F2N6O2S |
|---|---|
| Molecular Weight | 703.675 |