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2109805-80-1

2109805-80-1 structure
2109805-80-1 structure
  • Name: BRD-4592
  • Chemical Name: BRD-4592
  • CAS Number: 2109805-80-1
  • Molecular Formula: C17H15FN2O
  • Molecular Weight: 282.318
  • Create Date: 2020-01-12 14:07:50
  • Modify Date: 2024-04-05 17:21:14
  • A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.

Name BRD-4592
Description A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.
References References 1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96. View Related Products by Target Bacterial
Molecular Formula C17H15FN2O
Molecular Weight 282.318