- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: K-777
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/500mg ￥Inquiry/10ml
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: K-777
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- DC Chemicals Limited
- China
- Product Name: K-777
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg $220.0/10ml
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
749860-43-3
749860-43-3 structure
- Name: K-777
- Chemical Name: K-777
- CAS Number: 749860-43-3
- Molecular Formula: C28H32F4IN5
- Molecular Weight: 641.5
- Create Date: 2020-01-20 15:54:56
- Modify Date: 2024-04-03 12:55:29
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K-777 is a potent and selective CCR4 antagonist that inhibits both CCL17 binding and CCL17-induced chemotaxis in Hut78 cells with IC50 of 57 and 8.9 nM respectively; induces CCR4 internalization, reduces cell surface CCR4.
| Name | K-777 |
|---|
| Description | K-777 is a potent and selective CCR4 antagonist that inhibits both CCL17 binding and CCL17-induced chemotaxis in Hut78 cells with IC50 of 57 and 8.9 nM respectively; induces CCR4 internalization, reduces cell surface CCR4. |
|---|---|
| References | References 1. Sato T, et al. Pharmacology. 2013;91(5-6):305-13. 2. Solari R, et al. Eur J Pharmacol. 2015 Sep 15;763(Pt B):169-77. View Related Products by Target Chemokine Receptor (CCR and CXCR) |
| Molecular Formula | C28H32F4IN5 |
|---|---|
| Molecular Weight | 641.5 |