K-777

Modify Date: 2024-04-03 12:55:29

K-777 Structure
K-777 structure
Common Name K-777
CAS Number 749860-43-3 Molecular Weight 641.5
Density N/A Boiling Point N/A
Molecular Formula C28H32F4IN5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of K-777


K-777 is a potent and selective CCR4 antagonist that inhibits both CCL17 binding and CCL17-induced chemotaxis in Hut78 cells with IC50 of 57 and 8.9 nM respectively; induces CCR4 internalization, reduces cell surface CCR4.

 Names

Name K-777

 K-777 Biological Activity

Description K-777 is a potent and selective CCR4 antagonist that inhibits both CCL17 binding and CCL17-induced chemotaxis in Hut78 cells with IC50 of 57 and 8.9 nM respectively; induces CCR4 internalization, reduces cell surface CCR4.
References References 1. Sato T, et al. Pharmacology. 2013;91(5-6):305-13. 2. Solari R, et al. Eur J Pharmacol. 2015 Sep 15;763(Pt B):169-77. View Related Products by Target Chemokine Receptor (CCR and CXCR)

 Chemical & Physical Properties

Molecular Formula C28H32F4IN5
Molecular Weight 641.5
Top Suppliers:I want be here



Get all suppliers and price by the below link:

K-777 suppliers

K-777 price