Name | PS 423 |
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Description | PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210; inhibits glucose uptake in C2C12 myoblasts; inhibits S6K but not PKB/Akt downstream signaling in muscle cells. |
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References | References 1. Busschots K, et al. Chem Biol. 2012 Sep 21;19(9):1152-63. 2. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14. View Related Products by Target PDK1 |
Molecular Formula | C25H23F3O9 |
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Molecular Weight | 524.445 |