PS 423
Modify Date: 2024-01-19 13:58:26
PS 423 structure
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Common Name | PS 423 | ||
|---|---|---|---|---|
| CAS Number | 1221964-37-9 | Molecular Weight | 524.445 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H23F3O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PS 423PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210; inhibits glucose uptake in C2C12 myoblasts; inhibits S6K but not PKB/Akt downstream signaling in muscle cells. |
| Name | PS 423 |
|---|
| Description | PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210; inhibits glucose uptake in C2C12 myoblasts; inhibits S6K but not PKB/Akt downstream signaling in muscle cells. |
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| References | References 1. Busschots K, et al. Chem Biol. 2012 Sep 21;19(9):1152-63. 2. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14. View Related Products by Target PDK1 |
| Molecular Formula | C25H23F3O9 |
|---|---|
| Molecular Weight | 524.445 |