PS 1145 dihydrochloride

Modify Date: 2024-01-05 18:14:04

PS 1145 dihydrochloride Structure
PS 1145 dihydrochloride structure
 Common Name PS 1145 dihydrochloride
CAS Number 1049743-58-9 Molecular Weight 395.670
Density N/A Boiling Point N/A
Molecular Formula C17H13Cl3N4O Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of PS 1145 dihydrochloride


PS-1145 (dihydrochloride) is a potent IκB kinase-2 inhibitor with an IC50 value of 88 nM. PS-1145 (dihydrochloride) inhibits activity of NF-κB by blocking IκB kinase phosphorylation in tumor-bearing rats[1].

 Names

Name N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)pyridine-3-carboxamide,dih ydrochloride
Synonym More Synonyms

 PS 1145 dihydrochloride Biological Activity

Description PS-1145 (dihydrochloride) is a potent IκB kinase-2 inhibitor with an IC50 value of 88 nM. PS-1145 (dihydrochloride) inhibits activity of NF-κB by blocking IκB kinase phosphorylation in tumor-bearing rats[1].
Related Catalog
Target

IC50: 88 nM (IκB kinase-2)[1]

References

[1]. Cernackova A, et al. Cachexia induced by Yoshida ascites hepatoma in Wistar rats is not associated with inflammatory response in the spleen or brain. J Neuroimmunol. 2019;337:577068.

 Chemical & Physical Properties

Molecular Formula C17H13Cl3N4O
Molecular Weight 395.670
Exact Mass 394.015503
PSA 74.16000
LogP 6.00480

 Synonyms

N-(6-Chloro-9H-β-carbolin-8-yl)nicotinamide dihydrochloride
3-Pyridinecarboxamide, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-, hydrochloride (1:2)
PS-1145 Dihydrochloride
Top Suppliers:I want be here

Get all suppliers and price by the below link:

PS 1145 dihydrochloride suppliers

PS 1145 dihydrochloride price

Related Compounds: More...
PS-1145
431898-65-6
PS-031291
1140493-04-4
PS 423
1221964-37-9
PS-432
2083630-26-4
4-[2-hydroxy-4-(4-hydroxy-2-methoxy-3,5,6-trimethylbenzoyl)oxy-3,5,6-trimethylbenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoic acid
158792-23-5
1,3-bis[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propan-2-ol,dihydrochloride
67931-87-7
M 1145 TFA
1172089-00-7
BMS-604992 dihydrochloride
1469750-46-6
2-aminohistamine dihydrochloride
89026-16-4
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1158522-08-7
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
940364-43-2
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
134104-43-1
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
131615-57-1
(4-Methyl-tetrahydro-furan-2-yl)-methanol
6906-52-1
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
930439-75-1
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
1018584-77-4
tert-Butyl-DL-alanine
1375289-11-4
5-(2,3,4-trifluorophenyl)-1H-pyrazol-3-amine
2148529-38-6
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
849349-65-1
Chemsrc provides PS 1145 dihydrochloride(CAS#:1049743-58-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PS 1145 dihydrochloride are included as well.>> amp version: PS 1145 dihydrochloride

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved