1414586-62-1

1414586-62-1 structure

Name: NSC 45576
Chemical Name: NSC 45576
CAS Number: 1414586-62-1
Molecular Formula: C₂₀H₁₄N₂O₄S
Molecular Weight: 378.402
Create Date: 2020-01-14 09:28:42
Modify Date: 2024-02-28 15:09:01
NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM; inhibits cAMP-induced EPAC activation while not affecting PKA activity; a valuable pharmacological tools for elucidating the biological functions of EPAC and for promoting an understanding of disease mechanisms related to EPAC/cAMP signaling.

Name	NSC 45576

Description	NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM; inhibits cAMP-induced EPAC activation while not affecting PKA activity; a valuable pharmacological tools for elucidating the biological functions of EPAC and for promoting an understanding of disease mechanisms related to EPAC/cAMP signaling.
References	References 1. Tsalkova T, et al. PLoS One. 2012;7(1):e30441. 2. Chen H, et al. J Med Chem. 2014 May 8;57(9):3651-65. 3. Mizuta K, et al. Respir Res. 2013 Sep 2;14:89. View Related Products by Target Other Targets

Molecular Formula	C₂₀H₁₄N₂O₄S
Molecular Weight	378.402